Exhaustion of racing sperm in nature-mimicking microfluidic channels during sorting.

نویسندگان

  • Savas Tasoglu
  • Hooman Safaee
  • Xiaohui Zhang
  • James L Kingsley
  • Paolo N Catalano
  • Umut Atakan Gurkan
  • Aida Nureddin
  • Emre Kayaalp
  • Raymond M Anchan
  • Richard L Maas
  • Erkan Tüzel
  • Utkan Demirci
چکیده

Fertilization is central to the survival and propagation of a species, however, the precise mechanisms that regulate the sperm's journey to the egg are not well understood. In nature, the sperm has to swim through the cervical mucus, akin to a microfluidic channel. Inspired by this, a simple, cost-effective microfluidic channel is designed on the same scale. The experimental results are supported by a computational model incorporating the exhaustion time of sperm.

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عنوان ژورنال:
  • Small

دوره 9 20  شماره 

صفحات  -

تاریخ انتشار 2013